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Burkhard Göke Selected Research

sodium-iodide symporter (sodium iodide symporter)

4/2015Mesenchymal stem cell-mediated, tumor stroma-targeted radioiodine therapy of metastatic colon cancer using the sodium iodide symporter as theranostic gene.
11/2013EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene.
8/2013Systemic image-guided liver cancer radiovirotherapy using dendrimer-coated adenovirus encoding the sodium iodide symporter as theranostic gene.
3/2013Stromal targeting of sodium iodide symporter using mesenchymal stem cells allows enhanced imaging and therapy of hepatocellular carcinoma.
12/2011Image-guided tumor-selective radioiodine therapy of liver cancer after systemic nonviral delivery of the sodium iodide symporter gene.
11/2011Sodium iodide symporter (NIS)-mediated radionuclide ((131)I, (188)Re) therapy of liver cancer after transcriptionally targeted intratumoral in vivo NIS gene delivery.
9/2011Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery.
4/2011Epidermal growth factor receptor-targeted (131)I-therapy of liver cancer following systemic delivery of the sodium iodide symporter gene.
1/2011Stimulation of retinoic acid-induced functional sodium iodide symporter (NIS) expression and cytotoxicity of ¹³¹I by carbamazepine in breast cancer cells.
10/2009Targeted radioiodine therapy of neuroblastoma tumors following systemic nonviral delivery of the sodium iodide symporter gene.
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Burkhard Göke Research Topics

Disease

47Neoplasms (Cancer)
01/2018 - 01/2002
27Crohn Disease (Crohn's Disease)
11/2014 - 08/2002
22Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2015 - 01/2004
18Ulcerative Colitis
01/2015 - 01/2004
17Colorectal Neoplasms (Colorectal Cancer)
09/2017 - 01/2002
17Inflammation (Inflammations)
01/2014 - 03/2004
15Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2016 - 06/2006
13Hepatocellular Carcinoma (Hepatoma)
01/2018 - 01/2002
12Type 2 Diabetes Mellitus (MODY)
11/2016 - 01/2002
8Neoplasm Metastasis (Metastasis)
04/2015 - 10/2005
7Body Weight (Weight, Body)
09/2015 - 11/2004
7Insulin Resistance
02/2015 - 01/2002
7Pancreatitis
11/2014 - 07/2004
7Colitis
01/2012 - 01/2004
6Liver Neoplasms (Liver Cancer)
08/2013 - 04/2011
5Necrosis
07/2014 - 01/2004
4Carcinoma (Carcinomatosis)
01/2016 - 01/2014
4Colonic Neoplasms (Colon Cancer)
04/2015 - 01/2003
4Pancreatic Neoplasms (Pancreatic Cancer)
02/2015 - 08/2012
4Carcinogenesis
01/2014 - 01/2002
4Atherosclerosis
06/2013 - 12/2007
4Edema (Dropsy)
01/2013 - 07/2004
4Liver Diseases (Liver Disease)
07/2011 - 03/2008
4Hypertension (High Blood Pressure)
11/2010 - 01/2004
3Obesity
05/2019 - 12/2007
3Carcinoid Tumor (Carcinoid)
12/2013 - 04/2011
3Weight Loss (Weight Reduction)
06/2013 - 08/2006
3Breast Neoplasms (Breast Cancer)
01/2011 - 01/2005
3Ileitis
11/2010 - 09/2007
3Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2010 - 05/2006
3Adenoma (Adenomas)
11/2010 - 01/2005
3Diabetes Mellitus
05/2010 - 01/2002
3Infections
08/2009 - 11/2005
3Hyperglycemia
12/2008 - 04/2002
3Hepatitis
03/2008 - 06/2005
3Neuroendocrine Carcinoma
05/2007 - 06/2006
2Pheochromocytoma
01/2015 - 07/2014
2Portal Hypertension
10/2013 - 06/2010

Drug/Important Bio-Agent (IBA)

16DNA (Deoxyribonucleic Acid)IBA
02/2016 - 02/2005
14sodium-iodide symporter (sodium iodide symporter)IBA
04/2015 - 08/2005
13Proteins (Proteins, Gene)FDA Link
01/2018 - 01/2005
13Messenger RNA (mRNA)IBA
09/2015 - 11/2005
11Glucose (Dextrose)FDA LinkGeneric
02/2015 - 01/2002
10Radioisotopes (Radionuclides)IBA
04/2015 - 10/2004
10Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2014 - 11/2004
8CytokinesIBA
01/2013 - 04/2006
7IodidesIBA
04/2015 - 11/2007
7LigandsIBA
12/2013 - 03/2008
7Therapeutic UsesIBA
03/2013 - 11/2005
6Insulin (Novolin)FDA Link
02/2015 - 01/2002
5Death Domain ReceptorsIBA
02/2016 - 09/2002
5Phosphotransferases (Kinase)IBA
02/2016 - 01/2007
5IncretinsIBA
11/2014 - 05/2002
5AntibodiesIBA
07/2014 - 08/2009
5LipidsIBA
06/2013 - 01/2002
5Biological ProductsIBA
03/2013 - 09/2007
5Infliximab (Remicade)FDA Link
08/2010 - 08/2002
4Glucagon-Like Peptide 1 (GLP 1)IBA
03/2014 - 05/2002
4ChemokinesIBA
03/2013 - 10/2005
4CeruletideIBA
01/2013 - 07/2004
4AmylasesFDA Link
01/2013 - 07/2004
4Interleukin-6 (Interleukin 6)IBA
01/2013 - 06/2006
4Peptides (Polypeptides)IBA
12/2011 - 05/2002
4Interleukin-8 (Interleukin 8)IBA
11/2010 - 03/2006
4beta CateninIBA
04/2009 - 01/2002
4Interleukin-22 (IL-22)IBA
03/2008 - 04/2006
3CateninsIBA
09/2017 - 11/2010
3Glucagon-Like Peptide-1 ReceptorIBA
02/2015 - 05/2002
3Pharmaceutical PreparationsIBA
02/2015 - 08/2005
3EverolimusFDA Link
01/2015 - 01/2007
3Metformin (Glucophage)FDA LinkGeneric
10/2014 - 09/2007
3Tretinoin (Retinoic Acid)FDA LinkGeneric
07/2014 - 05/2008
3Heat-Shock Proteins (Heat-Shock Protein)IBA
12/2013 - 07/2004
3Peroxidase (Myeloperoxidase)IBA
01/2013 - 06/2006
3EndocannabinoidsIBA
01/2013 - 08/2008
3Somatostatin Receptors (Somatostatin Receptor)IBA
01/2013 - 05/2002
3TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
01/2013 - 11/2010
3Biomarkers (Surrogate Marker)IBA
08/2012 - 11/2011
3Dextran SulfateIBA
01/2012 - 04/2006
3Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
11/2011 - 01/2007
3TrypsinIBA
11/2011 - 07/2004
3Triglycerides (Triacylglycerol)IBA
11/2010 - 09/2006
3Azathioprine (Imuran)FDA LinkGeneric
08/2009 - 08/2002
3AdiponectinIBA
01/2009 - 05/2006
2BilirubinIBA
01/2018 - 01/2012
2Calcibiotic Root Canal SealerIBA
11/2016 - 02/2005
2Chemokine CCL5IBA
04/2015 - 03/2013
2HSP27 Heat-Shock ProteinsIBA
02/2015 - 08/2012
2GemcitabineFDA Link
02/2015 - 08/2012
2Lovastatin (Mevacor)FDA LinkGeneric
01/2015 - 07/2014
2Toll-Like Receptors (Toll-Like Receptor)IBA
12/2013 - 03/2008
2Dendrimers (Dendrons)IBA
11/2013 - 08/2013
2Cannabinoid Receptors (Cannabinoid Receptor)IBA
10/2013 - 01/2013

Therapy/Procedure

44Therapeutics
05/2019 - 01/2002
4Gamma Cameras (Gamma Camera)
03/2013 - 11/2007
3Precision Medicine
04/2015 - 08/2013
3Glycemic Control
02/2015 - 01/2002
3Drug Therapy (Chemotherapy)
07/2011 - 01/2007
3Ligation
06/2010 - 09/2002
3Biological Therapy
05/2007 - 06/2006